Tadalafil: What You Need to Know

Tadalafil, best known by the brand name Cialis, is a medicine people use for erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and sometimes pulmonary arterial hypertension (as Adcirca). It belongs to a group called PDE5 inhibitors. If you're curious how it helps and what to watch for, this short guide gives clear, practical facts so you can talk to a clinician with confidence.

How tadalafil works and common uses

Tadalafil relaxes blood vessels and increases blood flow to certain areas of the body. For ED that means it helps get and keep an erection when you’re sexually stimulated. For BPH it can ease urinary symptoms like frequent or weak streams. For pulmonary arterial hypertension, a higher-dose version helps lower pressure in the lungs.

Two ways people take it: "as-needed" and "daily." As-needed doses (usually 5–20 mg) are taken before sex and can last up to 36 hours — that’s why some call it the "weekend pill." Daily dosing (usually 2.5–5 mg) gives a steady effect so you don’t have to time a dose around sex. Your healthcare provider will suggest which approach fits you.

Dosing, interactions and safety tips

Typical starting doses: 10 mg before sex or 2.5–5 mg once daily for continuous use. Older adults or those with kidney or liver issues often start lower. Never mix tadalafil with nitrates (used for chest pain) — the combo can cause a dangerous drop in blood pressure. Be careful with alpha-blockers for prostate or blood pressure too; spacing doses or adjusting therapy is common practice.

Common side effects are headache, flushing, indigestion, back pain, and stuffy nose. Most are mild and short-lived. If you get sudden vision loss, hearing changes, or an erection lasting more than four hours, seek emergency care immediately.

Drug interactions matter: nitrates, some blood pressure meds, and strong grapefruit juice can cause issues. If you take medicines for HIV, hepatitis C, or certain antibiotics or antifungals, dosage adjustments may be needed. Always tell your clinician about every medicine and supplement you use.

Buying tips: only buy from licensed pharmacies. Look for clear contact info, pharmacy license, and secure checkout. Avoid suspiciously low prices that require bypassing prescriptions. If you order online, keep a copy of the prescription and check packaging for tampering when it arrives.

Storage and simple care: keep tablets in the original package at room temperature and out of reach of children. Don’t crush extended-release versions. If you miss a daily dose, take it when you remember but don’t double up.

Tadalafil can work well, but it’s not right for everyone. If you have heart disease, low blood pressure, or take nitrates, mention it to your provider. Ask questions about dosing and interactions so you can use tadalafil safely and effectively.